发明名称 |
AZATRICYCLIC ANTIBIOTIC COMPOUNDS |
摘要 |
The invention relates to antibacterial compounds of formula I (I) wherein n is 0 or 1; R1 represents H or F; U represents CH2 or, provided n is 1, O or NH; "---- " is a bond or is absent; V represents CH or N when "---- " is a bond, or CH2 or NH when "---- " is absent; W represents CH or N; A represents -(CH2)p-NH-(CH2)q- wherein p is 1 and q is 1 or 2 or, provided U represents CH2 and n is 1, p may also be 0 and q is then 2; G represents one of the groups (II) (III) wherein Z represents N or CH and Q represents O or S; and Z0, Z1 and Z2 each represent CH, or Z0 and Z1 each represent CH and Z2 represents N, or Z0 represents CH, Z1 represents N and Z2 represents CH or N, or Z0 represents N and Z1 and Z2 each represent CH; and to salts of such compounds |
申请公布号 |
WO2009104147(A2) |
申请公布日期 |
2009.08.27 |
申请号 |
WO2009IB50675 |
申请日期 |
2009.02.19 |
申请人 |
ACTELION PHARMACEUTICALS LTD;HUBSCHWERLEN, CHRISTIAN;RUEEDI, GEORG;SURIVET, JEAN-PHILIPPE;ZUMBRUNN ACKLIN, CORNELIA |
发明人 |
HUBSCHWERLEN, CHRISTIAN;RUEEDI, GEORG;SURIVET, JEAN-PHILIPPE;ZUMBRUNN ACKLIN, CORNELIA |
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