摘要 |
A conjugate which comprises a cyclosporin moiety of formula (I) linked to one or more mitochondrial targeting groups, or a pharmaceutically acceptable salt thereof: wherein: A represents or, B represents methyl or ethyl, one Of R1 and R1* represents hydrogen and the other represents methyl, R2 represents ethyl or isopropyl, R3 represents hydrogen or methyl, and R4 represents—CH2CH(CH3)CH3,—CH2CH(CH3)CH2CH3,—CH(CH3)CH3 or—CH(CH3)CH2CH3. |