ADENYLATE DEAMINASE CONTAINING HIDROGEL AND USE THEREOF FOR THE TREATMENT OF DERMAL WOUNDS (ULCERS)

摘要

This invention relates to pharmacology, particularly to drug production and compositions of medical means which contains components of natural microbiological origin, which promote healing of dermal wounds (ulcers). The object of this invention is use of Penicillium lanoso-viride adenylate deaminase (AMP aminohydrolase, E.C. 3.5.4.6.) in manufacturing drug, especially gel for treatment of dermal wounds (ulcers), as well as manufacturing adenylate deaminase containing hydrogel composition. Offered hydrogel contain from 0,3 till 3,0 (U)/ml units of adenylate deaminase. Offered hydrogel promote healing of wounds, this is experimentally proved comparing with one of in Latvia registered gels for the treatment of wounds and ulcers which is set on base of Carbopol polymer.