发明名称 |
Heteroaryl compounds, compositions thereof, and their use as protein kinase inhibitors |
摘要 |
Provided herein are Heteroaryl Compounds having the following structure:
wherein R 1 , R 2 , L, X, Y, Z, Q, A and B are as defined herein, compositions comprising an effective amount of a Heteroaryl Compound and methods for treating or preventing cancer, inflammatory conditions, immunological conditions, metabolic conditions and conditions treatable or preventable by inhibition of a kinase pathway comprising administering an effective amount of a Heteroaryl Compound to a patient in need thereof. |
申请公布号 |
EP2090577(A2) |
申请公布日期 |
2009.08.19 |
申请号 |
EP20090006829 |
申请日期 |
2007.10.18 |
申请人 |
SIGNAL PHARMACEUTICALS LLC |
发明人 |
MORTENSEN, DEBORAH SUE;MEDEROS, MARIA MERCEDES DELGADO;SAPIENZA, JOHN JOSEPH;ALBERS, RONALD J.;LEE, BRANDON G;HARRIS, ROY LEONARD LLL;SHEVLIN, GRAZIELLA ISABEL;HUANG, DEHUA;SCHWARZ, KIMBERLEY LYN;PACKARD, GARRICK K.;PARNES, JASON SIMON;PAPA, PATRICK WILLIAM;TEHRANI, LIDA RADNIA;PERRIN-NINKOVIC, SOPHIE;RIGGS, JENNIFER R. |
分类号 |
C07D471/04;A61K31/4985;A61P35/00;C07D487/04;C07D498/04 |
主分类号 |
C07D471/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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