| 摘要 |
<p>A preparation for use against skin tumours, which preparation has a semi-solid consistency for enabling the preparation to be applied to and remain on a patient's skin during treatment of a tumour on the patient's skin; which preparation comprises bleomycin which acts against the tumour, an elastic liposome which entraps the bleomycin; and a bleomycin containing carrier which contains the bleomycin in the elastic liposome; and which preparation is such that: (i) the concentration of the bleomycin in the bleomycin containing carrier is not less than the concentration of the bleomycin in the elastic liposome; (ii) the concentration of the bleomycin in the bleomycin containing carrier is not so great as to cause the bleomycin in the bleomycin containing carrier to leak into the elastic liposome and cause the elastic liposome to burst; and (iii) the external concentration of the bleomycin in the bleomycin containing carrier is such that it maintains an osmotic balance between internal and external environments of the elastic liposome whereby the internal concentration of the bleomycin in the elastic liposome is kept constant.</p> |
