发明名称 Pyrrolo(oxo)isoquinolines as 5HT ligands
摘要 The present application describes compounds according to Formula I, pharmaceutical compositions, comprising at least one compound according to Formula I and optionally at least one additional therapeutic agent and methods of treating various diseases, conditions and disorders associated with modulation of serotonin receptors such as, for example: metabolic diseases, which includes but is not limited to obesity, diabetes, diabetic complications, atherosclerosis, impaired glucose tolerance and dyslipidemia; central nervous system diseases which includes but is not limited to, anxiety, depression, obsessive compulsive disorder, panic disorder, psychosis, schizophrenia, sleep disorder, sexual disorder and social phobias; cephalic pain; migraine; and gastrointestinal disorders using compounds according to Formula I or pharmaceutically acceptable salt forms thereof, wherein A, B, D, E, m, n, R3, R7, R8, R9, R10, R11 and X are described herein.
申请公布号 US7572805(B2) 申请公布日期 2009.08.11
申请号 US20050180268 申请日期 2005.07.13
申请人 BRISTOL-MYERS SQUIBB COMPANY 发明人 FEVIG JOHN M.;FENG JIANXIN;AHMAD SALEEM
分类号 A61K31/44;C07D471/00 主分类号 A61K31/44
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