发明名称 |
METHOD FOR PREPARING STIRIPENTOL PARTICLE WITH PRESCRIBED PARTICLE SIZE DISTRIBUTION |
摘要 |
PROBLEM TO BE SOLVED: To provide a method for preparing stiripentol particles with a prescribed particle size distribution in a high yield which can be carried out at an industrial scale. SOLUTION: The method for preparing the stiripentol particles comprises: (i) a step of dissolving stiripentol in an aromatic solvent, (ii) a step of crystallizing stiripentol from the solvent, and (iii) recovering the resulting stiripentol particles. Recrystallization of stiripentol from the aromatic solvent enables achievement of prescribed particle size distribution without requiring subsequent pulverizing and/or screening steps. The method enables production of a high-purity product. COPYRIGHT: (C)2009,JPO&INPIT |
申请公布号 |
JP2009173655(A) |
申请公布日期 |
2009.08.06 |
申请号 |
JP20090012254 |
申请日期 |
2009.01.22 |
申请人 |
BIOCODEX |
发明人 |
HUBLOT BERNARD;BERTHON CEDILLE LAURENCE;LEGUERN MARIE-EMMANUELLE;RENUD GILLES |
分类号 |
C07D317/54;A61K31/36;A61P25/00;A61P25/08 |
主分类号 |
C07D317/54 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|