INHIBITORS OF LENTIVIRAL REPLICATION

摘要

The present invention provides peptides having lentiviral replication inhibiting properties, more in particular having antiviral activities with respect to HIV (Human Immunodeficiency Virus). The invention further relates to the use of said peptides as a medicine and in the manufacture of a medicament useful for the treatment of subjects suffering from a HIV infection, as well as for treatment of other lentiviral infections and to the treatment of animals suffering from FIV or lentiviral infections. The invention also relates to pharmaceutical compositions comprising said peptides. The invention also provides methods of treatment or prevention of a lentiviral infection in a mammal. The invention also relates to corresponding nucleic acid sequences encoding said peptides, to constructs comprising said corresponding nucleic acid sequences and to compositions thereof useful for the prevention or treatment of lentiviral, more in particular HIV infections in mammals.