发明名称 |
Four-dimensional (4D) image verification in respiratory gated radiation therapy |
摘要 |
A method for four-dimensional (4D) image verification in respiratory gated radiation therapy, includes: acquiring 4D computed tomography (CT) images, each of the 4D CT images representing a breathing phase of a patient and tagged with a corresponding time point of a first surrogate signal; acquiring fluoroscopic images of the patient under free breathing, each of the fluoroscopic images tagged with a corresponding time point of a second surrogate signal; generating digitally reconstructed radiographs (DRRs) for each breathing phase represented by the 4D CT images; generating a similarity matrix to assess a degree of resemblance in a region of interest between the DRRs and the fluoroscopic images; computing a compounded similarity matrix by averaging values of the similarity matrix across different time points of the breathing phase during a breathing period of the patient; determining an optimal time point synchronization between the DRRs and the fluoroscopic images by using the compounded similarity matrix; and acquiring a third surrogate signal and turning a treatment beam on or off according to the optimal time point synchronization.
|
申请公布号 |
US7570738(B2) |
申请公布日期 |
2009.08.04 |
申请号 |
US20070831090 |
申请日期 |
2007.07.31 |
申请人 |
SIEMENS MEDICAL SOLUTIONS USA, INC.;SIEMENS AKTIENGESELLSCHAFT |
发明人 |
KHAMENE ALI;FLORIN CHARLES HENRI;CELI JUAN CARLOS;OFSTAD BARBARA;ROUSSON MIKAEL;SAUER FRANK;SCHALLER CHRISTIAN |
分类号 |
A61N5/10;A61B6/02;A61B6/03 |
主分类号 |
A61N5/10 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|