| 摘要 |
An IL-1&bgr; binding molecule, in particular an antibody to human IL-1&bgr;, especially a human antibody to human IL-1&bgr; is provided, wherein the CDRs of the heavy and light chains have amino acid sequences as defined, for use in the treatment of an IL-1 mediated disease or disorder, e.g. osteoarthritis, osteoporosis and other inflammatory arthritides.
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