发明名称 |
ANTI-TUMOR AGENT FOR GASTROINTESTINAL CANCER |
摘要 |
Disclosed are a novel medicinal agent, a novel health food and the like, each of which comprises a short peptide as an active ingredient, which is safe, inexpensive and effective, and which has a novel anti-tumor effect, wherein the short peptide is derived from a probiotic (an enterobacterium which lives symbiotically in a human intestine) and can be chemically synthesized readily. Specifically disclosed are an activator for an insulin-like growth factor-binding protein and an anti-tumor agent for gastrointestinal cancer including colorectal cancer, each of which comprises plantaricin-A (one of bacteriocins) secreted from Lactobacillus plantarum and composed of 26 amino acid residues or CSF (competence and sporulation factor) secreted from Bacillus subtilis and composed of 5 amino acid residues as an active ingredient. |
申请公布号 |
WO2009093447(A1) |
申请公布日期 |
2009.07.30 |
申请号 |
WO2009JP00207 |
申请日期 |
2009.01.21 |
申请人 |
NATIONAL UNIVERSITY CORPORATION ASAHIKAWA MEDICALCOLLEGE;FUJIYA, MIKIHIRO;KOHGO, YUTAKA;OKAMOTO, KOTARO |
发明人 |
FUJIYA, MIKIHIRO;KOHGO, YUTAKA;OKAMOTO, KOTARO |
分类号 |
A61K38/00;A23L1/305;A61K35/74;A61K48/00;A61P35/00;A61P43/00;C07K14/32;C07K14/335 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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