摘要 |
A compound having the structure (I) wherein R is an angiotensin receptor antagonist active group, Y is selected from the group consisting of (II), and 2) -C(R1H)OC(O)X((CR12R13)-(CHR10)m-(CH2)n-Zp-(CH2)q-(CHR11)r-(CR16R17))-R5; Z is O- or (CR14R15)-; m, n, p, q, and r are independently selected from the group consisting of 0 and 1; X is O- or (CR18R19)-; R1 is selected from the group consisting of hydrogen, C1-4 alkyl, aryl and C1-4 alkylaryl; R5 is -O-N=N(O)-NR3R4; or a pharmaceutically acceptable salt or hydrate thereof, which is useful for treating hypertension.
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