| 发明名称 |
ENANTIOMERICALLY RESOLVING ACYLOXYALKYL THIOCARBONATES USED IN SYNTHESIZING ACYLOXYALKYL CARBAMATE PRODRUGS |
| 摘要 |
Methods of enzymatically resolving acyloxyalkyl thiocarbonates useful in the synthesis of acyloxyalkyl carbamates are disclosed. These carbamates can be coupled to drugs containing amines such as R-baclofen or S-pregabalin.
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| 申请公布号 |
CA2706575(A1) |
申请公布日期 |
2009.07.30 |
| 申请号 |
CA20092706575 |
申请日期 |
2009.01.23 |
| 申请人 |
XENOPORT, INC. |
发明人 |
GALLOP, MARK A.;YAO, FENMEI;LUDWIKOW, MARIA J.;PENG, GE;RAILLARD, STEVEN P. |
| 分类号 |
C07B57/00;C07C269/04;C07C271/22;C07C329/06;C07D207/46;C12P41/00 |
主分类号 |
C07B57/00 |
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