| 发明名称 |
IN VIVO TRANSFORMATION OF PANCREATIC ACINAR CELLS INTO INSULIN-PRODUCING CELLS |
| 摘要 |
<p>The present invention includes compositions and methods for transforming cells into glucose-responsive, insulin-production cells using a construct that expresses betacellulin and PDX1, e.g., transforming pancreatic acinar cells using one or more expression vectors that expressed betacellulin and PDX1 using ultrasound targeted microbubble destruction (UTMD).</p> |
| 申请公布号 |
EP2082036(A2) |
申请公布日期 |
2009.07.29 |
| 申请号 |
EP20070843023 |
申请日期 |
2007.09.21 |
| 申请人 |
BAYLOR RESEARCH INSTITUTE |
发明人 |
GRAYBURN, PAUL, A.;CHEN, SHUYUAN |
| 分类号 |
C12N15/00;C07H21/02;C07H21/04;C12N5/00;C12N5/02 |
主分类号 |
C12N15/00 |
| 代理机构 |
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