| 发明名称 |
DIAGNOSIS OF ALZHEIMER'S DISEASE BASED ON MITOGEN-ACTIVATED PROTEIN KINASE PHOSPHORYLATION |
| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a method of diagnosing Alzheimer's disease of a patient. <P>SOLUTION: The method includes the step of determining whether a phosphorylation level of an indicator protein in a patient's cell has abnormally rises from a basic phosphorylation level after stimulated by an activator compound, wherein the indicator protein is Erk1/2 for example and the activator compound is bradykinin for example. <P>COPYRIGHT: (C)2009,JPO&INPIT |
| 申请公布号 |
JP2009148247(A) |
申请公布日期 |
2009.07.09 |
| 申请号 |
JP20080286869 |
申请日期 |
2008.11.07 |
| 申请人 |
BLANCHETTE ROCKEFELLER NEUROSCIENCES INST |
发明人 |
ALKON DANIEL L;ZHAO WEI-QIN |
| 分类号 |
C12Q1/48;G01N33/50;A61K45/00;A61P25/28;A61P43/00;C12N5/10;C12N9/99;C12Q1/02;G01N33/15;G01N33/53;G01N33/68 |
主分类号 |
C12Q1/48 |
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