| 发明名称 |
RAF INHIBITOR COMPOUNDS AND METHODS |
| 摘要 |
Pyrazolyl compounds of Formulas Ia and Ib are useful for inhibiting Raf kinase and for treating disorders mediated thereby. Methods of using pyrazolyl compounds for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.
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| 申请公布号 |
US2009176809(A1) |
申请公布日期 |
2009.07.09 |
| 申请号 |
US20080347412 |
申请日期 |
2008.12.31 |
| 申请人 |
LAIRD ELLEN;LYSSIKATOS JOSEPH P;WELCH MIKE;GRINA JONAS;HANSEN JOSH;NEWHOUSE BRAD;OLIVERO ALAN;TOPALOV GEORGE |
发明人 |
LAIRD ELLEN;LYSSIKATOS JOSEPH P.;WELCH MIKE;GRINA JONAS;HANSEN JOSH;NEWHOUSE BRAD;OLIVERO ALAN;TOPALOV GEORGE |
| 分类号 |
A61K31/4439;A61K31/4545;A61K31/506;A61P35/00;C07D401/04;C07D401/14;C07D487/04 |
主分类号 |
A61K31/4439 |
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