发明名称 |
DIAGNOSTIC IN VITRO METHOD FOR ASSESSING VON WILLEBRAND DISEASE AND INCREASED BLEEDING RISK ASSOCIATED WITH VON WILLEBRAND DISEASE AND ACQUIRED OR CONGENITAL DISORDERS OF PLATELETFUNCTION |
摘要 |
The invention relates to an in-vitro method for diagnosing Von Willebrand Disease (VWD) and an increased bleeding risk associated with von Willebrand Disease and/or acquired or congenital platelet function defects which reduce the interaction of von Willebrand Factor (VWF) with platelets. The in-vitro method of the invention may also be used to diagnose further bleeding risks. The test is suitable for use as a screening test based on whole blood and has the additional benefit of being suitable as a point of care test. The method involves the incubation of a sample containing platelets and haemostasis factors with an activator of platelet aggregation and the measurement of the viscoelastic change after inducing coagulation, e.g. by means of thromboelastography (TEG).
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申请公布号 |
CA2710340(A1) |
申请公布日期 |
2009.07.02 |
申请号 |
CA20082710340 |
申请日期 |
2008.12.19 |
申请人 |
CSL BEHRING GMBH |
发明人 |
TOPF, HANS-GEORG;RAUH, MANFRED |
分类号 |
G01N33/86 |
主分类号 |
G01N33/86 |
代理机构 |
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