发明名称 METHODS AND COMPOSITIONS FOR INHIBITING UNDESIRABLE CELLULAR PROLIFERATION BY TARGETED LIPOSOME DELIVERY OF ACTIVE AGENTS
摘要 Provided are methods for inhibiting undesirable proliferation of a tumor cell or a tumor in a subject including administering to the subject a composition that includes an effective amount of an active agent, wherein the active agent is entrapped by one or more liposomes, the active agent has activity in inhibiting undesirable proliferation of the tumor cell or the tumor, and the one or more liposomes include one or more targeting agents that preferentially or specifically bind to a binding molecule expressed by the tumor cell or the tumor, present on the tumor cell or the tumor, present in the tumor cell or the tumor, or combinations thereof. Also provided are compositions for treating tumors, particularly gliomas, in a subject in need thereof.
申请公布号 US2009162425(A1) 申请公布日期 2009.06.25
申请号 US20080234282 申请日期 2008.09.19
申请人 UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 发明人 DIVI MURALI KRISHNA;WOOD GEORGE C.;GABER M. WALEED;THOMA LAURA
分类号 A61K9/127;A61K31/337;A61P35/04 主分类号 A61K9/127
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