发明名称 |
Bimatoprost crystalline form I |
摘要 |
The invention provides a novel polymorphic form I of crystalline bimatoprost, method for preparation thereof and new crystalline intermediates in the preparation. This form I of crystalline bimatoprost is used in purification of crude bimatoprost and in storage of bimatoprost as active pharmaceutical intermediate. Use of the physical form of bimatoprost in the manufacture of a medicament is also disclosed.
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申请公布号 |
US2009163596(A1) |
申请公布日期 |
2009.06.25 |
申请号 |
US20070896002 |
申请日期 |
2007.08.29 |
申请人 |
GUTMAN ARIE;RUKHMAN IGOR;TISHIN BORIS;YUDOVICH LEV;VILENSKY ALEXANDER;PERTSIKOV BORIS;NISNEVICH GENNADY |
发明人 |
GUTMAN ARIE;RUKHMAN IGOR;TISHIN BORIS;YUDOVICH LEV;VILENSKY ALEXANDER;PERTSIKOV BORIS;NISNEVICH GENNADY |
分类号 |
A61K31/165;A61P27/02;C07C231/24;C07C235/34;C07F7/18 |
主分类号 |
A61K31/165 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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