摘要 |
A partially purified product of a hyaluronic acid salt obtained from a culture of a microorganism capable of producing hyaluronic acid, preferably a microorganism belonging to the genus Streptcoccus, is brought into contact with a solution containing a salt and a hydrophilic organic solvent, thereby transferring to a liquid phase, impurities contained in said partially purified product such as proteins, nucleic acids, colorants, endotoxins and the like, and then isolating the hyaluronic acid salt as a precipitate. |