发明名称 |
Mammalian checkpoint proteins polypeptides and encoding sequences thereof |
摘要 |
The present invention relates to the isolation of gene sequences encoding mammalian cell cycle checkpoints, as well as the expression of the encoded proteins using recombinant DNA technology. The expressed proteins are used to generate specific antibodies and to inhibit the growth of cells. The human checkpoint gene sequences are used as a probe for a portion of the chromosome associated with tumors and other malignancies, as well as growth and/or development deficiencies.
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申请公布号 |
USRE40789(E1) |
申请公布日期 |
2009.06.23 |
申请号 |
US20020267717 |
申请日期 |
2002.10.09 |
申请人 |
BAYLOR COLLEGE OF MEDICINE |
发明人 |
ELLEDGE STEPHEN J.;SANCHEZ YOLANDA |
分类号 |
C12N9/12;A61K38/00;C07K1/00;C07K14/47;C12N9/10 |
主分类号 |
C12N9/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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