发明名称 Pyrimidine derivatives useful as inhibitors of PKC-theta
摘要 Disclosed are novel compounds of formula (I): wherein R1, R2 and R3 are as defined herein, which are useful as inhibitors of PKC-theta and are thus useful for treating a variety of diseases and disorders that are mediated or sustained through the activity of PKC-theta, including immunological disorders and type II diabetes. This invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.
申请公布号 US7550473(B2) 申请公布日期 2009.06.23
申请号 US20040933635 申请日期 2004.09.03
申请人 BOEHRINGER INGELHEIM PHARMACEUTICALS, INC.;BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG 发明人 CARDOZO MARIO G.;COGAN DEREK;CYWIN CHARLES LAWRENCE;DAHMANN GEORGE;DISALVO DARREN;GINN JOHN DAVID;PROKOPOWICZ, III ANTHONY S.;SPERO DENICE M.;YOUNG ERICK RICHARD ROUSH
分类号 C07D239/42;A61K31/505;A61K31/506;A61P3/10;A61P37/00;C07D239/48;C07D401/12;C07D401/14;C07D403/12;C07D405/12;C07D409/12;C07D471/04;H01L51/00 主分类号 C07D239/42
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