发明名称 TREATMENT OF MULTIPLE SCLEROSIS (MS) WITH CAMPATH-1H.
摘要 <p>A method for treatment of multiple sclerosis (MS) with Campath-1H with significant efficacy and a favourable safety profile is described, which offers an acceptable benefit/risk ratio. Especially described is the use of Campath-1H (alemtuzumab) for the production of a medicament for the treatment of multiple sclerosis (MS), comprising a first treatment cycle followed by at least one further treatment cycle of Campath-1H (alemtuzumab), in which each treatment cycle comprises 1-5 daily doses which are applied on consecutive days, wherein the daily dose is >0 and ⿤ 12 mg, and wherein each treatment cycle is separated from the next cycle by at least 1 - 24 months. Also described are treatment regimens comprising the administration of less than 12 mg/day of Campath-1H for a period of 1-5 consecutive days.</p>
申请公布号 MX2009002660(A) 申请公布日期 2009.06.11
申请号 MX20090002660 申请日期 2007.09.11
申请人 BAYER SCHERING PHARMA AKTIENGESELLSCHAFT 发明人 ANDREAS SACHSE;DAVID HARRIS MARGOLIN
分类号 A61K39/395;A61K31/502;A61P15/00;C07D401/04;C07K16/28 主分类号 A61K39/395
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