发明名称 PROCESSES FOR PREPARING A SUBSTITUTED GAMMA-AMINO ACID
摘要 The present invention is related to processes suitable for industrial synthesis of pregabalin from (i?)-(-)-3-(carbamoylmethyl)-5-methylhexanoic using sodium hypochlorite as described herein. In addition, the present invention is related to pregabalin which is substantially free of impurities and pharmaceutical compositions comprising pregabalin.
申请公布号 CA2706381(A1) 申请公布日期 2009.06.04
申请号 CA20082706381 申请日期 2008.11.25
申请人 MEDICHEM, S.A. 发明人 MANGION, BERNARDINO
分类号 C07C227/04;A61K31/195;A61P29/00;C07C229/08 主分类号 C07C227/04
代理机构 代理人
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