发明名称 |
Method for producing basic amino acid |
摘要 |
When a basic amino acid is produced by culturing a microorganism having an ability to produce the basic amino acid in a liquid medium under an aerobic condition to produce and accumulate the basic amino acid in the medium, pH of the medium is controlled to be 6.5-9.0 during the culture, and 7.2-9.0 at the end of the culture, and a culture period where 2 g/L or more of hydrogencarbonate ions and/or carbonate ions exist in the medium is secured during the culture by controlling pressure in a fermentation tank to be a positive pressure during the fermentation, or supplying carbon dioxide gas or a mixed gas containing carbon dioxide gas to the medium, so that the hydrogencarbonate ions and/or carbonate ions should serve as counter ions of cations mainly consisting of the basic amino acid. |
申请公布号 |
EP2065471(A1) |
申请公布日期 |
2009.06.03 |
申请号 |
EP20090001098 |
申请日期 |
2001.08.23 |
申请人 |
AJINOMOTO CO., INC. |
发明人 |
KOBAYASHI, MASAKI;ITOYAMA, TSUYOSHI;MITANI, YUKIO;USUI, NAOKI |
分类号 |
C12P13/04;C12P13/08;C07C229/26;C07C229/28;C07D233/64;C12P13/10;C12P13/24;C12R1/13 |
主分类号 |
C12P13/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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