摘要 |
The present invention features polypeptides capable of catalyzing a ligation reaction between a first RNA molecule comprising, e.g., a hydroxyl group at the 3' position and a second RNA molecule comprising, e.g., a triphosphate group at the 5' position. The invention further features methods of selecting, optimizing, and using such polypeptides.
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申请人 |
THE GENERAL HOSPITAL CORPORATION;SEELIG, BURCHARD;SZOSTAK, JACK, W.;KEEFE, ANTHONY, D.;CHO, GLEN, S. |
发明人 |
SEELIG, BURCHARD;SZOSTAK, JACK, W.;KEEFE, ANTHONY, D.;CHO, GLEN, S. |