发明名称 METHODS FOR THE DIRECTED EXPANSION OF EPITOPES FOR USE AS ANTIBODY LIGANDS
摘要 The instant invention comprises a process for selecting and manufacturing antibodies useful for therapeutic, prophylactic, diagnostic or research purposes using epitope peptide mixtures synthesized by the solid phase synthesis, such process defined by a set of rules regarding the identity and the frequency of occurrence of amino acids that substitute a base or native amino acid of a known epitope. The resulting antibodies are related to but distinct from antibodies that bind to the known epitope.
申请公布号 WO2009023047(A3) 申请公布日期 2009.05.28
申请号 WO2008US05919 申请日期 2008.05.07
申请人 PEPTIMMUNE, INC.;BONNIN, DUSTAN 发明人 BONNIN, DUSTAN
分类号 A61K39/145;C07K1/04 主分类号 A61K39/145
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