| 摘要 |
<p>Disclosed are carboxamide, sulfonamide and amine compounds, as well as pharmaceutical compositions and methods of use. One embodiment is a compound having the structure in which R1, R2, R4, E, T, n and x are as described herein. In certain embodiments, a compound disclosed herein activates the AMPK pathway, and can be used to treat metabolism-related disorders and conditions.</p> |
| 申请人 |
RIGEL PHARMACEUTICALS, INC.;HONG, HUI;XU, XIANG;YU, JIAXIN;SINGH, RAJINDER;DARWISH, IHAB, S.;THOTA, SAMBAIAH |
发明人 |
HONG, HUI;XU, XIANG;YU, JIAXIN;SINGH, RAJINDER;DARWISH, IHAB, S.;THOTA, SAMBAIAH |
