REMOTELY TRIGGERED RELEASE FROM HEATABLE SURFACES

摘要

The present invention provides means of remotely and/or controllably releasing an agent to be delivered (e.g. therapeutic, diagnostic, prophylactic, and/or nutraceutical agent). In general, heatable surfaces which heat in response to external stimuli (e.g. electromagnetic (EM) fields, light, etc.) are provided. Heatable surfaces are typically associated with one or more agents to be delivered via thermally-responsive linkers. When the resulting thermally-responsive conjugate is subjected to an external stimulus (e.g. EM field, light), heatable surfaces release a certain amount of heat. The amount of heat released may or may not be sufficient to disrupt the function of the thermally-responsive linker, resulting in release of the agent to be delivered.