发明名称 SUBSTITUTED BETA-PHENYL-ALPHA-HYDROXY-PROPANOIC ACID, SYNTHESIS METHOD AND USE THEREOF
摘要 The present invention relates to a compound of the formula (I), wherein R1, R2 and R3 are each independently selected from H, OH, F, Cl, Br, methoxy and ethoxy; or alternatively, R1 and R2 together form -OCH2O-, R3 is selected from H, OH, methoxy, ethoxy and halogens; R4 is OH or acyloxy; R5 is cycloalkoxyl, amino and substituted amino, and when R5 is selected from amino, at least one of R1, R2 and R3 is not H. The present invention further relates to a process for synthesizing a compound of the formula (I), and use of the compound of the formula (I) in the manufacture of a medicament for the prevention or treatment of cardiovascular or cerebrovascular diseases.
申请公布号 US2009131677(A1) 申请公布日期 2009.05.21
申请号 US20070301069 申请日期 2007.05.14
申请人 NORTHWEST UNIVERSITY 发明人 ZHENG XIAOHUI;ZHANG QUNZHENG;WANG SHIXIANG;ZHAO XINFENG
分类号 C07D213/79;C07C69/612 主分类号 C07D213/79
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