发明名称 |
IMMUNOGENIC POLYPEPTIDE COMPOSED OF TUMOR ANTIGEN-DERIVED OPTIMIZED CRYPTIC PEPTIDES, AND USES THEREOF |
摘要 |
The present invention pertains to the field of anti-cancer vaccines. More particularly, the invention concerns an optimized polypeptide, which comprises three cryptic tumor peptides with enhanced immunogenicity and comprises the amino acids sequence YLQVNSLQTVYLEYRQVPVYLEEITGYL, for use in an anti-cancer vaccine. Nucleic acids encoding such a polypeptide, as well as complexes and dendritic cells engineered with this polypeptide or a nucleic acid encoding it, are also part of the invention.
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申请公布号 |
US2009130133(A1) |
申请公布日期 |
2009.05.21 |
申请号 |
US20080158736 |
申请日期 |
2008.10.16 |
申请人 |
KOSMATOPOULOS KOSTANTINOS;CORNET SEBASTIEN |
发明人 |
KOSMATOPOULOS KOSTANTINOS;CORNET SEBASTIEN |
分类号 |
A61K39/00;C07K7/00;C07K14/00;C12N5/06;C12N15/00;C12N15/11 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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