发明名称 |
Hybrid Hepatocyte Growth Factor Gene Having High Expression Efficiency of Two Heterotypes of Hepatocyte Growth Factor |
摘要 |
The present invention relates to a hybrid Hepatocyte Growth Factor (HGF) gene which is prepared by inserting an inherent or foreign intron between exons 4 and 5 in HGF cDNA, which has a base sequence of SEQ ID NO: 2. The gene has high expression efficiency and simultaneously expresses two heterotypes of HGF and dHGF (deleted variant HGF). Further the gene may be used for treating or preventing ischemic or liver diseases.
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申请公布号 |
US2009131350(A1) |
申请公布日期 |
2009.05.21 |
申请号 |
US20070957170 |
申请日期 |
2007.12.14 |
申请人 |
VIROMED, CO., LTD. |
发明人 |
KIM JONG-MOOK;HAHN WOONG |
分类号 |
A61K31/7088;C12N15/09;A61K35/76;A61K38/00;A61K48/00;A61P1/16;A61P9/10;C07K14/475;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/12 |
主分类号 |
A61K31/7088 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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