发明名称 Specific therapy using integrin ligands for treating cancer
摘要 The invention relates to a combination therapy for the treatment of tumors and tumor metastases comprising administration of integrin ligands, preferably integrin antagonists, together with co-therapeutic agents or therapy forms that have synergistic efficacy when administered consecutively with said ligands, such as chemotherapeutic agents and or radiation therapy. The therapy results in a synergistic potential increase of the inhibition effect of each individual therapeutic on tumor cell proliferation, yielding more effective treatment than found by administering an individual component alone, concurrently or not in the dosage regime of the present invention.
申请公布号 US2009130098(A1) 申请公布日期 2009.05.21
申请号 US20070161195 申请日期 2007.01.18
申请人 MERCK PATENT GMBH 发明人 GOODMAN SIMON;PICARD MARTIN ANDREAS;MIKKELSEN TOM;NIPPGEN JOHANNES;GRIMM ULRIKE;STUPP ROGER;WELLER MICHAEL;HARSTRICK ANDREAS;GRELL MATTHIAS
分类号 A61K39/395;A61K38/12;A61P35/00 主分类号 A61K39/395
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