THERAPEUTIC PRO-APOPTOTIC BH3-LIKE MOLECULES AND METHODS FOR GENERATING AND/OR SELECTING THE SAME
摘要
The present invention relates generally to therapeutic molecules which are useful for modulating apoptosis in a target cell or cell population. More particularly, the present invention provides therapeutic agents which inhibit pro-survival molecules and which are capable of inducing or facilitates apoptosis of a target cell or cell population such as cancer cells. Further provided are methods for generating or selecting the therapeutic molecules and pharmaceutical compositions comprising the therapeutic molecules.
申请公布号
EP1910535(A4)
申请公布日期
2009.05.20
申请号
EP20060752632
申请日期
2006.06.23
申请人
THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH
发明人
COLMAN, PETER, MALCOLM;HUANG, DAVID, CHING, SIANG;LEE, ERINNA, FAITH;FAIRLIE, WALTER, DOUGLAS