| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a device, an implant and a method, that obviate the need for asmixture of osteogenic protein with matrix, repairing bone deletion, cartilage defect and/or bone, cartilage defect. <P>SOLUTION: Provided herein are methods for inducing bone formation in a mammal sufficient to fill a defect defining a void, wherein osteogenic protein is provided alone or dispersed in a biocompatible non-rigid, amorphous carrier having no defined surfaces. The methods and devices provide injectable formulations for filling critical size defects, as well as for accelerating the rate and enhancing the quality of bone formation in non-critical size defects. <P>COPYRIGHT: (C)2009,JPO&INPIT |
