| 发明名称 |
DEVELOPMENT OF MOLECULAR IMAGING PROBES FOR CARBONIC ANHYDRASE-IX USING CLICK CHEMISTRY |
| 摘要 |
The present application discloses methods for identifying inhibitors with high binding-affinity for the carbonic anhydrase-IX (CA-IX) enzyme using click chemistry and uses the candidates thereof as positron emission tomography (PET) imaging agents.
|
| 申请公布号 |
US2009123372(A1) |
申请公布日期 |
2009.05.14 |
| 申请号 |
US20080099135 |
申请日期 |
2008.04.07 |
| 申请人 |
SIEMENS MEDICAL SOLUTIONS USA, INC. |
发明人 |
KOLB HARTMUTH C.;WALSH JOSEPH C.;KASI DHANALAKSHMI;MOCHARLA VANI P.;WANG BING;GANGADHARMATH UMESH B.;DUCLOS BRIAN A.;CHEN KAI;ZHANG WEI;CHEN GANG;PADGETT HENRY CLIFTON;KARIMI FARHAD;SCOTT PETER J. H.;GAO ZHIYONG;LIANG QIANWA;COLLIER THOMAS LEE;ZHAO TIEMING;XIA CHUNFANG |
| 分类号 |
C07D249/04;A61K49/04;A61K51/04;C07D413/12 |
主分类号 |
C07D249/04 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
