发明名称 Simplified biological evaluation method of natural and artificial chemicals by using DNA injury index and apparatus therefor
摘要 A biological evaluation method for rational and simply evaluating biological harmfulness or usefulness of a great number of natural and artificial chemicals, foods, etc. This method comprises adding a known amount of 2'-deoxyguanosine (dG) to a solution containing a test substance (drug, pesticide, functional food, etc.), optionally applying UV light and/or adding active oxygen generator, then quantifying 8-hydroxy-2'-deoxyguanosine (8OHdG) in the solution, and evaluating the toxicity or usefulness of the test substance according to the 8OhdG content (a higher 8OhdG content indicates a higher harmfulness of the test substance while a lower 8OhdG content indicates a lower harmfulness or an usefulness thereof). The invention also provide an apparatus for advantageously performing said biological evaluation method and an antioxidant preservative solution to be used in this apparatus.
申请公布号 US7531312(B2) 申请公布日期 2009.05.12
申请号 US20050311360 申请日期 2005.12.20
申请人 TAS PROJECT CO., LTD.;KYUSHU TLO COMPANY, LIMITED 发明人 TAKAKI ATSUSHI
分类号 G01N33/53;C07H11/00;C12Q1/02;C12Q1/68;G01N33/50;G01N33/52 主分类号 G01N33/53
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