发明名称 |
Chimeric alphavirus replicon particles |
摘要 |
Chimeric alphaviruses and alphavirus replicon particles are provided including methods of making and using same. Specifically, alphavirus particles are provided having nucleic acid molecules derived from one or more alphaviruses and structural proteins (capsid and/or envelope) from at least two or more alphaviruses. Methods of making, using, and therapeutic preparations containing the chimeric alphavirus particle, are disclosed.
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申请公布号 |
US7531180(B2) |
申请公布日期 |
2009.05.12 |
申请号 |
US20020123101 |
申请日期 |
2002.04.11 |
申请人 |
NOVARTIS VACCINES AND DIAGNOSTICS, INC |
发明人 |
POLO JOHN M.;PERRI SILVIA;THUDIUM KENT |
分类号 |
A61K39/12;C12N15/09;A61K35/76;A61K38/00;A61K39/193;A61K48/00;A61P37/04;C07K14/18;C12N5/10;C12N7/00;C12N7/01;C12N15/86 |
主分类号 |
A61K39/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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