| 发明名称 |
USPA1 AND USPA2 ANTIGENS OF MORAXELLA CATARRHALIS |
| 摘要 |
The present invention discloses the existence of two novel proteins UspA1 and UspA2, and their respective genes uspA1 and uspA2. Each protein encompasses a region that is conserved between the two proteins and comprises an epitope that is recognized by the MAb 17C7. One or more than one of these species may aggregate to form the very high molecular weight form (i.e. greater than 200 kDa) of the UspA antigen. Compositions and both diagnostic and therapeutic methods for the treatment and study of M. catarrhalis are disclosed.
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| 申请公布号 |
US2009118486(A1) |
申请公布日期 |
2009.05.07 |
| 申请号 |
US20080044805 |
申请日期 |
2008.03.07 |
| 申请人 |
HANSEN ERIC J;AEBI CHRISTOPH;COPE LESLIE D;MACIVER ISOBEL;FISKE MICHAEL J;FREDENBURG ROSS A |
发明人 |
HANSEN ERIC J.;AEBI CHRISTOPH;COPE LESLIE D.;MACIVER ISOBEL;FISKE MICHAEL J.;FREDENBURG ROSS A. |
| 分类号 |
C07H21/00;C12N15/09;A61K38/00;A61K39/00;A61K39/09;A61P31/04;C07K14/00;C07K14/21;C07K16/12;C12Q1/68 |
主分类号 |
C07H21/00 |
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