发明名称 |
PURIFICATION OF ANTIBODIES CONTAINING HYDROPHOBIC VARIANTS |
摘要 |
<p>The present invention encompasses methods of purifying samples containing antibodies. In particular the present invention provides methods of reducing hydrophobic variants in these samples using a series of column chromatography steps, comprising protein A affinity chromatography, ion exchange chromatography and hydrophobic interaction chromatography.</p> |
申请公布号 |
WO2009058769(A1) |
申请公布日期 |
2009.05.07 |
申请号 |
WO2008US81438 |
申请日期 |
2008.10.28 |
申请人 |
SCHERING CORPORATION;BLAISDELL, STEVEN, J. |
发明人 |
BLAISDELL, STEVEN, J. |
分类号 |
C07K1/16;C07K1/36;C07K16/24 |
主分类号 |
C07K1/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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