HYBRID MICROFLUIDIC SPR AND MOLECULAR IMAGING DEVICE
摘要
A hybrid microfluidic biochip designed to perform multiplexed detection of singled- celled pathogens using a combination of SPR and epi-fluorescence imaging. The device comprises an array of gold spots, each functionalized with a capture biomolecule targeting a specific pathogen. This biosensor array is enclosed by a polydimethylsiloxane (PDMS) microfluidic flow chamber that delivers a magnetically concentrated sample to be tested. The sample is imaged by surface plasmon resonance on the bottom of the biochip, and epi- fluorescence on the top.
申请公布号
WO2009058853(A2)
申请公布日期
2009.05.07
申请号
WO2008US81571
申请日期
2008.10.29
申请人
PURDUE RESEARCH FOUNDATION;LEARY, JAMES, F.;PARK, KINAM;ACHARYA, GHANASHYAM;ZORDAN, MICHAEL
发明人
LEARY, JAMES, F.;PARK, KINAM;ACHARYA, GHANASHYAM;ZORDAN, MICHAEL