发明名称 |
METHODS OF REDUCING CELL DEATH FOLLOWING HYPOXIA / REOXYGENATION |
摘要 |
Provided are methods of reducing cell death, attenuating a burst of reactive oxygen species, reducing cytotoxicity, reducing intracellular oxidant stress due species in a population of cells following hypoxia by reoxygenating the cells in the presence of a reversible electron transport chain inhibitor or under hypercarbic conditions. Also provided is a method to determine the effectiveness of a reversible electron transport chain inhibitor for reducing cell death in a population of cells.
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申请公布号 |
US2009110673(A1) |
申请公布日期 |
2009.04.30 |
申请号 |
US20070302140 |
申请日期 |
2007.05.25 |
申请人 |
THE UNIVERSITY OF CHICAGO |
发明人 |
VANDEN HOEK TERRY L.;SHAO ZUO-HUI;LI CHANG-QING;BEISER DAVID G.;BECKER LANCE |
分类号 |
A61K31/7084;A01N1/02;A61K31/192;A61K31/27;A61K31/352;C12N5/06;C12N9/99;C12Q1/02 |
主分类号 |
A61K31/7084 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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