METHOD FOR ENANTIOSELECTIVE HYDROGENATION OF CHROMENES
摘要
A method for preparing an enantiomeric chromane, by asymmetrically hydrogenating a chromene compound in the presence of an Ir catalyst having a chiral ligand. The method includes the enantioselective preparation of enantiomeric equol. A preferred Ir catalyst has a chiral phosphineoxazoline ligand. Enantiomeric chromanes of high stereoselective purity can be obtained.
申请公布号
WO2007016423(A3)
申请公布日期
2009.04.30
申请号
WO2006US29589
申请日期
2006.08.01
申请人
GIRINDUS AMERICA INC.;CHILDREN'S HOSPITAL MEDICAL CENTER;SETCHELL, KENNETH DAVID REGINALD;SOROKIN, VICTOR, DMITRIEVICH
发明人
SETCHELL, KENNETH DAVID REGINALD;SOROKIN, VICTOR, DMITRIEVICH