发明名称 METHOD FOR EFFICIENT PRODUCTION OF MONOCYTE-DERIVED MULTIPOTENT CELL (MOMC)
摘要 <p>The object is to provide a practical method that can produce an MOMC, which is a multipotent cell highly suitable for the cell transplantation for organ regeneration, efficiently and in a large quantity. It is found that an MOMC can be produced more efficiently by conducting the in vitro culture of a peripheral blood monocyte on a fibronectin in the presence of SDF-1. Thus, disclosed is a method for producing an MOMC by conducting the in vitro culture of a peripheral blood monocyte capable of expressing CD14 on a fibronectin, wherein the in vitro culture is carried out in the presence of SDF-1.</p>
申请公布号 WO2009054128(A1) 申请公布日期 2009.04.30
申请号 WO2008JP02990 申请日期 2008.10.22
申请人 KEIO UNIVERSITY;KUWANA, MASATAKA;KATO, TAKASHI;SETA, NORIYUKI;MIYAZAKI, HIROSHI 发明人 KUWANA, MASATAKA;KATO, TAKASHI;SETA, NORIYUKI;MIYAZAKI, HIROSHI
分类号 A61K35/12;A61K38/19;A61L27/00;A61P9/00;A61P19/00;A61P25/28;C07K14/52;C12N5/0789;G01N33/15;G01N33/50 主分类号 A61K35/12
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