| 发明名称 |
PROCESS FOR THE PRODUCTION OF TERT-BUTYL (E)-(6- 2- 4-(4-FLUOROPHENYL)-6-ISOPROPYL-2- METHYL(METHYLSULFONYL)AMINO PYRIMIDIN-5-YL VINYL (4R,6S)-2,2-DIMETHYL 1,3 DIOXAN-4-YL)ACETATE |
| 摘要 |
<p>The invention concerns a process for the manufacture of tert-butyl (E)-(6-[2-4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]vinyl)-(4R, 6S)-2,2-dimethyl(1,3-dioxan-4-yl) acetate, the novel starting material used in said process and the use of the process in the manufacture of a pharmaceutical.</p> |
| 申请公布号 |
SI1155015(T1) |
申请公布日期 |
2009.04.30 |
| 申请号 |
SI20000031016T |
申请日期 |
2000.02.15 |
| 申请人 |
ASTRAZENECA AB;SHIONOGI & CO., LTD. |
发明人 |
KOIKE HARUO;KABAKI MIKIO;TAYLOR NIGEL PHILIP;DIORAZIO LOUIS JOSEPH |
| 分类号 |
A61K31/505;A61P3/06;A61P9/00;A61P9/10;C07D239/00;C07D239/42;C07D319/06;C07D319/08;C07D405/06;C07F9/53;C07F9/6512 |
主分类号 |
A61K31/505 |
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