发明名称 MEDICINAL COMPOSITIONS QUICKLY DISINTEGRATING IN THE ORAL CAVITY AND PROCESS FOR PRODUCING THE SAME
摘要 This invention relates to a medicinal composition, which rapidly disintegrates when taken in the oral cavity and shows sufficient hardness upon production, distribution and use in usual manner, can be obtained by adding, to a sugar alcohol and/or saccharide, a sugar alcohol and/or saccharide having a lower melting point than the first-mentioned sugar alcohol and/or saccharide and then subjecting the resulting powder to combined processing of compression and heating. This invention can provide medicinal compositions, which rapidly disintegrate when taken in the oral cavity without water and are excellent in handling ease owing to exhibition of sufficient hardness upon their production, transportation and use in usual manner, and can also provide a process for the production of the medicinal compositions, which is simpler and can avoid contact between an active ingredient and water as needed.
申请公布号 EP1334716(A4) 申请公布日期 2009.04.29
申请号 EP20010974848 申请日期 2001.10.15
申请人 DAIICHI PHARMACEUTICAL CO., LTD. 发明人 NAKAGAMI, HIROAKI;KUNO, YOSHIO
分类号 A61K9/00;A61K9/20;A61K31/135;A61K31/166;A61K31/167;A61K31/216;A61K31/401;A61K31/404;A61K31/405;A61K31/43;A61K31/4422;A61K31/455;A61K31/4704;A61K31/51;A61K31/513;A61K31/515;A61K31/5513;A61K31/606 主分类号 A61K9/00
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