发明名称 |
METHOD FOR SCREENING FOR VITAMIN D RECEPTOR LIGAND |
摘要 |
The present invention relates to a screening method for a compound and includes a step of detecting binding between a vitamin D receptor and CDP. A novel method enabling screening in vitro of a compound having strong bone forming action and low side effects, a compound participating in osteoblast differentiation and selected by the method of screening, a therapeutic agent containing the compound for diseases intervening in the increase in vitamin D-mediated transcriptional activity by a complex of a vitamin D receptor and CDP, and a kit for performing the screening method are provided.
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申请公布号 |
EP2053130(A1) |
申请公布日期 |
2009.04.29 |
申请号 |
EP20070791983 |
申请日期 |
2007.07.30 |
申请人 |
THE UNIVERSITY OF TOKYO;TEIJIN PHARMA LIMITED |
发明人 |
OCHIAI, EIJI;YAMAOKA, KAZUYOSHI;TAKAGI, KEN-ICHIRO;TSUSHIMA, YU;KATO, SHIGEAKI;KITAGAWA, HIROCHIKA;TAKADA, ICHIRO |
分类号 |
C12Q1/68;C12N15/09;C12Q1/02;G01N33/15;G01N33/50 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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