发明名称 Phospholipid derivatives and process for the production there
摘要 A phospholipid derivative represented by the following formula (1): wherein [PG]k represents a residue of polyglycerin having a polymerization degree of k, wherein k is 2 to 50, R1CO and R2CO independently represent an acyl group having 8 to 22 carbon atoms, symbol "a" independently represents an integer of 0 to 5, symbol "b" independently represents 0 or 1, M represents hydrogen atom, an alkali metal atom, an ammonium, or an organic ammonium, and k1, k2, and k3 represent numbers satisfying the following conditions: 1<=k1<=(k+2)/2, 0<=k2, and k1+k2+k3=k+2. The phospholipid derivative is highly safe for living bodies and can be suitably utilized in drug delivery systems such as liposome, and the like.
申请公布号 US7524981(B2) 申请公布日期 2009.04.28
申请号 US20030541309 申请日期 2003.12.12
申请人 NOF CORPORATION;DAIICHI PHARMACEUTICAL CO., LTD. 发明人 KUBO KAZUHIRO;ITOH CHIKA;OHHASHI SYUNSUKE;YASUKOHCHI TOHRU;OHKAWA YUSUKE;KIKUCHI HIROSHI;SUZUKI NORIO;TAKAHASHI MIHO;YAMAUCHI HITOSHI
分类号 C07C9/02;A61K8/14;A61K8/55;A61K9/127;A61K47/24;A61P35/00;A61Q19/00;C07F9/10;C08G65/26;C08G65/335 主分类号 C07C9/02
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