METHOD AND DEVICE FOR STRENGTHENING SYNAPTIC CONNECTIONS

摘要

The invention provides a method and device for inducing a conditioned neural response in a subject. The method comprises detecting spike activity in a first neural sit e in the subject; and delivering a stimulus pulse to a second neural site in the subject. The stimulus pulse is delivered within the time window for synaptic strengthening following the detecting of a spike. These two steps, detection and stimulation, are repeated continuously, typically for a day or two. The conditioned neural response is induced when a pattern of neural activity evoked by stimulation at the first neural site emulates a pattern of neural activity evoked by stimulation at the second neural site. The conditioned neural response persists for an extended period of time.