| 发明名称 |
Compounds leading to an increase of the IL-12/IL-10 ratio and their use for therapy of infectious and proliferative diseases |
| 摘要 |
<p>Described is the treatment of immunologically relevant diseases such as infections or a proliferative disease, in particular cancer, by increasing the IL-12/IL-10 ratio caused by the sequential administration of lipopeptides (e.g., FSL-1, FSL-2 or OspA-Lp) and lipopolysaccharides (e.g., LPS R60) alone or in combination with IFN-³.</p> |
| 申请公布号 |
EP2050455(A1) |
申请公布日期 |
2009.04.22 |
| 申请号 |
EP20070020351 |
申请日期 |
2007.10.18 |
| 申请人 |
DC GESELLSCHAFT FUER DENTRITIC-CELL-THERAPIE MBH |
发明人 |
LORENZEN, DIRK;NESSELHUT, THOMAS;PETERS, J. HINRICH;WIESMUELLER, KARL-HEINZ;FREUDENBERG, MARINA A.;GALANOS, CHRIS;BESSLER, WOLFGANG G. |
| 分类号 |
A61K31/715;A61K38/08;A61P35/00;A61P37/04 |
主分类号 |
A61K31/715 |
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